[2-(2,4-DICHLOROPHENYL)-2-HYDROXYETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER
N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanamine
CAS: 939757-30-9
Molecular Formula: C13H17Cl2NO3
[2-(2,4-DICHLOROPHENYL)-2-HYDROXYETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER - Names and Identifiers
[2-(2,4-DICHLOROPHENYL)-2-HYDROXYETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER - Physico-chemical Properties
| Molecular Formula | C13H17Cl2NO3 |
| Molar Mass | 306.18 |
| Solubility | DCM, Ethyl Acetate |
| Appearance | Oil |
| Color | Colourless |
[2-(2,4-DICHLOROPHENYL)-2-HYDROXYETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER - Introduction
N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanamine is an organic compound with the chemical formula C12H16Cl2NO3.
Nature:
-Appearance: Colorless or white crystalline solid.
-Solubility: Soluble in organic solvents such as ether, chloroform and dimethylformamide.
-Melting point: about 70-72 degrees Celsius.
Use:
The compound is often used in organic synthesis, as an intermediate to participate in a variety of chemical reactions. Specific uses include but are not limited:
-Drug research: can be used as a key intermediate for the synthesis of peptidomimetic drugs.
-Organic synthesis: Participate in reactions such as the construction of carbon-carbon bonds and the introduction of functional groups.
Method:
Generally, the preparation of N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanamine can be carried out by the following steps:
1. The reaction of 2,4-dichlorobenzyl alcohol and dimethylformamide generates 2-(2,4-dichlorophenyl) acetamide.
2.2-(2,4-dichlorophenyl) acetamide and tert-butyl dimethylcarbamate (Boc2O) are reacted under the catalysis of a base to generate N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanamine.
Safety Information:
-This compound may be harmful to health and may irritate the respiratory system, skin and eyes.
-When using or handling this compound, take protective measures, such as wearing protective glasses, gloves and dust masks.
-Keep away from heat sources, open flames and oxidants to avoid fire.
-When using or handling this compound, pay attention to a well-ventilated environment.
Nature:
-Appearance: Colorless or white crystalline solid.
-Solubility: Soluble in organic solvents such as ether, chloroform and dimethylformamide.
-Melting point: about 70-72 degrees Celsius.
Use:
The compound is often used in organic synthesis, as an intermediate to participate in a variety of chemical reactions. Specific uses include but are not limited:
-Drug research: can be used as a key intermediate for the synthesis of peptidomimetic drugs.
-Organic synthesis: Participate in reactions such as the construction of carbon-carbon bonds and the introduction of functional groups.
Method:
Generally, the preparation of N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanamine can be carried out by the following steps:
1. The reaction of 2,4-dichlorobenzyl alcohol and dimethylformamide generates 2-(2,4-dichlorophenyl) acetamide.
2.2-(2,4-dichlorophenyl) acetamide and tert-butyl dimethylcarbamate (Boc2O) are reacted under the catalysis of a base to generate N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanamine.
Safety Information:
-This compound may be harmful to health and may irritate the respiratory system, skin and eyes.
-When using or handling this compound, take protective measures, such as wearing protective glasses, gloves and dust masks.
-Keep away from heat sources, open flames and oxidants to avoid fire.
-When using or handling this compound, pay attention to a well-ventilated environment.
Last Update：2024-04-09 02:00:49
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Product Name: [2-(2,4-DICHLORO-PHENYL)-2-HYDROXY-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER Visit Supplier Webpage Request for quotation
CAS: 939757-30-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 939757-30-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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